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Dr. Holzman was a professor both in the Psychology and Psychiatry Departments at Harvard starting in 1977. Teaching, however, was not Dr. Holzman's only love. His long and varied research career focused on psychophysiological abnormalities, particularly eye movements and spatial working memory as they relate to schizophrenia. These studies resulted in numerous papers on the subject. Dr. Holzman was a preeminent figure in the world of schizophrenia research.

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Among Dr. Holzman's other research interests are the effects of self-confrontation; the etiology of thyroid "hot spots"; and psychotherapy's role in treating mental illness, particularly schizophrenia.

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